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December 2016

Volume 2  Issue 1

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Research Article

A Pilot Study on Health-Related Quality of Life and Caregiving Burden of Caregivers for Dementia: A Cross-sectional Report on the Pre-Test Assessment Results

Thomas T.H. Wan, Ph.D., MHS,* An Sun, MD, and Adam Golden, MD, MBA

Alzheimer’s disease (AD), an irreversible and progressive disease, is the fourth leading cause of deaths among the elderly in the U.S., following deaths from heart disease, cancer, and stroke. The number of people with AD is expected to reach 12 million in the U.S. Although AD has been better understood from clinical studies, the pathogenesis of AD is not clearly identified. Generally, AD results from brain cell atrophy and death of brain cells due to abnormal accumulation of plagues and neurofibrillary tangles in the nerve cells. Unfortunately, there are no effective treatments or drugs that can completely cure it or delay the occurrence of AD.

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Review article

Nutrition and the Role of Tube Feeding in the Elderly

Si Ching LIM* MB. ChB (Bristol UK), MRCP (UK), Jeannie PL ONG MBBS, MRCP (UK) , CH Poh, MBBS, MRCP, Christopher TC Lien MBBS, FRCP (Edin), FAMS

As the population ages, more elderly patients will come in contact with the medical profession. Malnutrition among the elderly is common and often, remains undetected by medical staff and carries serious implications for general poor health, increased morbidity, mortality, mortality, prolonged hospital stay, poor wound healing, pressure sores and increasing costs. Early assessment of the nutritional status among older people is, therefore, important to identify those who are malnourished or at risk of malnutrition in order to reduce the further decline in weight, physical function and quality of life.

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Research article

Ultrasound Determined Muscle Quality is Associated with Neuromuscular Fatigue and Mobility in Older Adults-A Pilot Study

Edward H. Robinson IV, Jeffrey R. Stout*, David H. Fukuda, Tyler C. Scanlon, Nadia S. Barnini, William P. McCormack, Gerald T. Mangine, Adam J. Wells, Kyle S. Beyer, Leonardo P. Oliveira, and Jay R. Hoffman

The purpose of this study was to examine the relationships of ultrasound-derived muscle quality with the onset of neuromuscular fatigue (NMF) and functional mobility in older adults. Fifteen older men and women (age: 70.7±7.3y; BMI: 27.3+5.6 kg.m-2) volunteered for this study. Cross-sectional area (CSA) and muscle thickness (MT) of the vastus lateralis (VL) were determined from ultrasound imaging, and echo intensity (EI) was determined by grayscale analysis using the standard histogram function in ImageJ. NMF was determined during a discontinuous incremental cycle ergometer test. Functional mobility was assessed using the get-up-and-go test (GUG).

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Research article

The Effects of Physical Activity Duration and Intensity on Age-Related Cognition

Christie Chung*, Julia A. Przemyslaw

In the present study, we examined how intensity and duration of physical activity might differentially affect age-related cognition. We utilized clear operational definitions of physical activity intensity and duration set forth by, and carefully instructed 35 older adults (56-93 years old) to complete a detailed 14-day journal packet of their daily activities. Fourteen of these older adults were participants in our research lab 6 years ago, therefore, we were able to examine cross-sectional as well as longitudinal data in this study. Our longitudinal and cross-sectional results suggest that while activity duration was associated with depression status; activity intensity was important for maintenance of cognitive health and social support in old age.

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